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Lumateperone tosylate
CAS No. 1187020-80-9
Lumateperone tosylate ( ITI-007 )
产品货号. M10638 CAS No. 1187020-80-9
Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥648 | 有现货 |
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| 25MG | ￥1320 | 有现货 |
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| 50MG | ￥1968 | 有现货 |
|
| 100MG | ￥2908 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Lumateperone tosylate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM).
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产品描述Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM); also shows affinity for D1; orally bioavailable and exhibits good antipsychotic efficacy in vivo.Schizophrenia Phase 3 Clinical
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同义词ITI-007
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域Neurological Disease
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适应症Schizophrenia
化学信息
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CAS Number1187020-80-9
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分子量565.70
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分子式C31H36FN3O4S
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCC1=CC=C(C=C1)S(=O)(=O)O.CN1CCN2C3CCN(CC3C4=C2C1=CC=C4)CCCC(=O)C5=CC=C(C=C5)F
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化学全称1-Butanone, 1-(4-fluorophenyl)-4-[(6bR,10aS)-2,3,6b,9,10,10a-hexahydro-3-methyl-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-, 4-methylbenzenesulfonate (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Li P, et al. J Med Chem. 2014 Mar 27;57(6):2670-82.
2. Snyder GL, et al. Psychopharmacology (Berl). 2015 Feb;232(3):605-21.
3. Davis RE, et al. Psychopharmacology (Berl). 2015 Aug;232(15):2863-72.
2. Snyder GL, et al. Psychopharmacology (Berl). 2015 Feb;232(3):605-21.
3. Davis RE, et al. Psychopharmacology (Berl). 2015 Aug;232(15):2863-72.
产品手册
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